PIK3CA anticorps (AA 409-613)

N° du produit ABIN5701188

Cet anticorps anti-PIK3CA est un anticorps Lapin Polyclonal détectant PIK3CA dans WB, IHC, ELISA, FACS et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour PIK3CA anticorps (AA 409-613) (ABIN5701188)

Antigène: PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIK3CA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP)

Détail du produit anti-PIK3CA anticorps

Épitope: AA 409-613

Fonction: PIK3CA antibody

Immunogène:

Immunogen sequence: 409-613aa

Immunogen: phosphoinositide-3-kinase, catalytic, alpha polypeptide

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:5000,IP:1:200-1:2000,IHC:1:100-1:400

Commentaires:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab06418(PIK3CA antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PIK3CA

Antigène: PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))

Autre désignation: PIK3CA

Sujet:

Synonyms: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha, PI3K-alpha, PI3Kalpha, PtdIns-3-kinase subunit alpha)|Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit p110-alpha, p110alpha)|Phosphoinositide 3-kinase alpha|Phosphoinositide-3-kinase catalytic alpha polypeptide|Serine/threonine protein kinase PIK3CA|PIK3CA

Background: Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4, 5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.

UniProt: P42336

Pathways: Signalisation PI3K-Akt, Signalisation RTK, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, VEGF Signaling